Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
Study Year1990
Molecular Weight of AgentLMW
Agent CategoryDiisocyanates
Specific AgentToluene diisocyanate (TDI)
Occupation Polyurethane foam workers (Includes cohort reported by Hendrick, 1986)
Outcome/DiagnosisOccupational asthma
Activity Intervention Transfer to low exposure area (5 years)
Participation Rate6 of 6 eligible subjects (Participation rate: 100%)
Intervention EffectivenessAll subjects (n=6) persisted with respiratory symptoms at follow-up, with no improvement in bronchial hyperresponsiveness. These subjects experienced significantly less exposures than workers on the foam line, and finishing workers (p<0.01).
Page last reviewed: February 20, 2020