Prevention of Work-related Asthma: Study Search

Prevention LevelSecondary
AuthorSaetta
Study Year1995
CountryItaly
Molecular Weight of AgentLMW
Agent CategoryDiisocyanates
Specific AgentToluene diisocyanate (TDI)
Occupation Workers in general population (Includes cohort reported by Saetta, 1992)
Outcome/DiagnosisOccuaptional asthma
Activity Intervention Removal from exposure (range: 6-21 months)
Participation RateLimitation: no report of participation rate
Intervention EffectivenessAt follow-up for 10 subjects, decreases were observed for sensitivity to TDI (p<0.05), thickness of subepithelial fibrosis (p<0.007), and numbers of subepithelial fibroblasts (p<0.05), mast cells (p<0.02), and lymphocytes (p<0.03) in comparison with values at diagnosis.
Page last reviewed: February 20, 2020