Primary |
Schweigert |
2000 |
Latin america, North America |
HMW |
Biological enzyme |
Detergent enzyme |
Detergent industry workers (Includes cohort reported by Peters, 1997) |
Occupational asthma |
Encapsulation of enzyme, compliance with operational enzyme guidelines, education and training, medical monitoring (use of skin prick test as screening method) |
Limitation: no report of participation rate |
Keeping rates of sensitization less than 3% per enzyme per year effectively eliminated new cases of OA since 1994, when this model was implemented, through 1997. Atopy exclusion had little impact. |