Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Anees
Study Year	2006
Country	UK
Molecular Weight of Agent	Both
Category	Various
Agent	Flour, latex, wood dust, isocyanates, metal, biocidal agents, colophony, oil mists
Occupation	Not specified
Outcome/Diagnosis	FEV1 decline in occupational asthma
Activity Intervention	Removal from exposure (at least 1 year)
Participation Rate	Limitation: no report of participation rate 156 subjects with occupational asthma.
Intervention Effectiveness	Only 90 subjects had FEV1 measurements for at least 1 year before removal from exposure (median 2.9 years). The mean (SE) rate of decline of these 90 subjects was 100.9 (17.7) ml/year. 114 subjects had FEV1 measurements for 1 year after removal from exposure, and their FEV1 had improved by a mean (SE) of 12.3(31.6) ml. 86 subjects had FEV1 measurements greater than 1 year (median 2.6 years, interquartile range (IQR) 1.7-4.6) after removal from exposure. The mean (SE) rate of FEV1 decline starting at 6 months after removal from exposure was 26.6 (18.0) ml/year for this group. The decline was not significantly worse in current smokers than in never smokers.