| Secondary |
| Labrecque M |
| 2011 |
| Canada |
| LMW |
| Diisocyanates |
| Diisocyanates |
| Various occupations (Workers exposed to diisocyanates) |
| Diisocyanate-induced occupational asthma (DiOA) |
| Medical surveillance program (MSP) for diisocyanate-induced occupational asthma. |
| 2897 workers answered the surveillance questionnaire (participation rate: 90%). |
| 20 workers (0.69% of 2897) with final diagnosis of DiOA in MSP (screened group) compared with 66 workers diagnosed with DiOA without participation in MSP (control group).
Two years after diagnosis and removal from exposure:
<ul><li>
The 20 subjects had a mean PC20 of 4.81 mg/ml significant higher than a mean PC20 of 1.67 mg/ml for control group.</li><li>
Clinical remission defined by a PC20 > 8 mg/ml and no anti-asthma medication was 34% for screened group significant different with 16% for control group.</li><li>
The median costs of compensation for functional impairment were significant lower with $C11893 in the screened group compared with $C19562 for the control group.</li><ul> |
