Primary |
Seaton |
1994 |
UK |
HMW |
Mold |
Aspergillus niger |
Workers manufacturing citric acid (Includes cohort reported by Topping, 1984) |
Occupational asthma |
Enclosure of process, exhaust ventilation, respirator use, education (1984) |
Original cohort: 101 of 261 eligible subjects (Participation rate: 39%) New workers: 37 of 76 eligible subjects (Participation rate: 49%) |
Before intervention, 18 of 343 workers were diagnosed with OA. No new cases of OA or specific skin sensitization occurred among original cohort with no symptoms in 1984 (n=90) or new workers surveyed in 1988 (n=34) who survived up through the last follow-up in 1991. |