Secondary |
Munoz X |
2014 |
Spain |
Both |
N/A |
N/A |
N/A |
Occupational asthma |
Cessation of exposure to the causative agents of high molecular weight (HMW) or low molecular weight (LMW). |
73 of 178 patients with occupational asthma and with a positive specific inhalation challenge were included in the study (Participation rate: 40%). 105 patients were excluded from data analysis because of no contact or refused to participate. |
Patients removed from exposure (n=55),
<ul>
<li> with cessation of HMW agent, statistically improved their symptoms of rhinitis, conjunctivitis and the percentage of eosinophils in blood p=0.002, 0.004, 0.018, respectively.</li>
<li> 47% had clinical improvement and 14% had deterioration on GINA severity sca</li>
</ul>
Patients continued to be exposed (n=18),
<ul>
<li> statistically deteriorated their symptoms of rhinitis and conjunctivitis p=0.039 and 0.012, respectivy</li>
<li> 22% had clinical improvement and 17% had deterioration on GINA severity scale.</li>
</ul> |