Prevention of Work-related Asthma: Study Search Results

Study Details
Prevention LevelSecondary
AuthorMunoz X
Study Year2014
Molecular Weight of AgentBoth
Outcome/DiagnosisOccupational asthma
Activity InterventionCessation of exposure to the causative agents of high molecular weight (HMW) or low molecular weight (LMW).
Participation Rate73 of 178 patients with occupational asthma and with a positive specific inhalation challenge were included in the study (Participation rate: 40%). 105 patients were excluded from data analysis because of no contact or refused to participate.
Intervention EffectivenessPatients removed from exposure (n=55), <ul> <li> with cessation of HMW agent, statistically improved their symptoms of rhinitis, conjunctivitis and the percentage of eosinophils in blood p=0.002, 0.004, 0.018, respectively.</li> <li> 47% had clinical improvement and 14% had deterioration on GINA severity sca</li> </ul> Patients continued to be exposed (n=18), <ul> <li> statistically deteriorated their symptoms of rhinitis and conjunctivitis p=0.039 and 0.012, respectivy</li> <li> 22% had clinical improvement and 17% had deterioration on GINA severity scale.</li> </ul>
Page last reviewed: May 25, 2022