Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Munoz X
Study Year	2014
Country	Spain
Molecular Weight of Agent	Both
Category	N/A
Agent	N/A
Occupation	N/A
Outcome/Diagnosis	Occupational asthma
Activity Intervention	Cessation of exposure to the causative agents of high molecular weight (HMW) or low molecular weight (LMW).
Participation Rate	73 of 178 patients with occupational asthma and with a positive specific inhalation challenge were included in the study (Participation rate: 40%). 105 patients were excluded from data analysis because of no contact or refused to participate.
Intervention Effectiveness	Patients removed from exposure (n=55), <ul> <li> with cessation of HMW agent, statistically improved their symptoms of rhinitis, conjunctivitis and the percentage of eosinophils in blood p=0.002, 0.004, 0.018, respectively.</li> <li> 47% had clinical improvement and 14% had deterioration on GINA severity sca</li> </ul> Patients continued to be exposed (n=18), <ul> <li> statistically deteriorated their symptoms of rhinitis and conjunctivitis p=0.039 and 0.012, respectivy</li> <li> 22% had clinical improvement and 17% had deterioration on GINA severity scale.</li> </ul>