Primary |
Bernstein |
1993 |
USA |
LMW |
Diisocyanates |
Diphenylmethane diisocyanate (MDI) |
Workers in a urethane mold plant |
Occupational asthma |
Plant design leading to reduction of exposure to MDI |
243 of 243 eligible subjects (Participation rate: 100%) |
Strict control and monitoring of ambient MDI exposure was associated with low prevalence of OA (3 of 243 subjects, 1.2%), which is less than the prevalence of 5% estimated in another plant with workers exposed to MDI. |