| Secondary |
| Goodno |
| 2002 |
| USA |
| HMW |
| Animal-derived antigens |
| Laboratory animal allergen |
| Laboratory animal handlers (Includes cohort reported by Fisher, 1998) |
| Laboratory animal allergy |
| Comprehensive prevention program (1991-2000): education and training, use of PPE, administrative controls, engineering controls, medical surveillance, and RAST testing for animal allergens |
| All employees who worked with laboratory animal(s) at least once a week were included in the study. Data was collected from 626 employees during the study period. Limitation: no report of participation rate |
| Of the 103 workers reporting LAA at entrance in the surveillance program, 39.8% reported allergies to two or more species. During the period of follow-up, 33% of workers with primary LAA reported the development of additional allergy. Annual incidence of secondary allergy ranged from 1.6% to 19.1% during the study period, greater than 8% in most years. |
