Secondary |
Malo |
1988 |
Canada |
HMW |
Animals, Crustacea, seafoods, fish |
Crab |
Snow crab-processing workers (Includes cohort reported by Cartier, 1984, Hudson, 1985) |
Occupational asthma |
Removal from exposure (FU mean: 12.8, 31.4, 64.4 months) |
Limitation: no report of participation rate |
Plateau of significant improvement was reached at mean 1 year follow-up for spirometry (p<0.01) and at the second follow-up for bronchial reactivity (p<0.05) compared to later follow-ups. There is concurrent reduction in IgE according to follow-up interval (p<0.01). |