Secondary |
Grammer |
1995 |
USA |
LMW |
Anhydrides |
hexahydrophthalic anhydride (HHPA) |
Workers who manufacture resin requiring use of HHPA |
Occupational asthma, allergic rhinitis, occupational asthma-rhinitis, hemorrhagic rhinitis |
Medical surveillance, removal from exposure (> 1 year) Medical surveillance consisted of symtpom questionnaire, spirometry, chest film, and immunological assays at diagnosis and at follow-up. |
Study population consisted of 16 employees consecutively identified over a 1-year surveillance period |
Symptoms or signs of occupational asthma/rhinitis or hemorrhagic rhinitis were nonexistent at follow-up, with no demonstration of obstruction (n=16). Chest films were normal, and reduction in IgE or IgG antibody was statistically significant. Limitation: no comparison group. |