Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Grammer
Study Year	1995
Country	USA
Molecular Weight of Agent	LMW
Category	Anhydrides
Agent	hexahydrophthalic anhydride (HHPA)
Occupation	Workers who manufacture resin requiring use of HHPA
Outcome/Diagnosis	Occupational asthma, allergic rhinitis, occupational asthma-rhinitis, hemorrhagic rhinitis
Activity Intervention	Medical surveillance, removal from exposure (> 1 year) Medical surveillance consisted of symtpom questionnaire, spirometry, chest film, and immunological assays at diagnosis and at follow-up.
Participation Rate	Study population consisted of 16 employees consecutively identified over a 1-year surveillance period
Intervention Effectiveness	Symptoms or signs of occupational asthma/rhinitis or hemorrhagic rhinitis were nonexistent at follow-up, with no demonstration of obstruction (n=16). Chest films were normal, and reduction in IgE or IgG antibody was statistically significant. Limitation: no comparison group.