Prevention of Work-related Asthma: Study Search Results

Study Details
Prevention LevelSecondary
Study Year1996
Molecular Weight of AgentLMW
Agenthexahydrophthalic anhydride (HHPA)
OccupationWorkers who manufacture resin requiring use of HHPA (Included cohort reported by Grammer, 1995)
Outcome/DiagnosisOccupational asthma, allergic rhinitis, occupational asthma-rhinitis, hemorrhagic rhinitis
Activity InterventionMedical surveillance, removal from exposure (> 1 year) Medical surveillance consisted of symtpom questionnaire, physical examination, spirometry, chest film, and immunological assays at diagnosis and at follow-up.
Participation RateStudy population consisted of 28 employees identified over a 4-year surveillance period
Intervention EffectivenessOf 28 subjects, symptoms and spirometry normalized in all except except one who had mild asthma. Statistically significant declines in IgE and IgG were also observed at follow-up. Limitation: no comparison group.
Page last reviewed: May 25, 2022