Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Grammer
Study Year	1996
Country	USA
Molecular Weight of Agent	LMW
Category	Anhydrides
Agent	hexahydrophthalic anhydride (HHPA)
Occupation	Workers who manufacture resin requiring use of HHPA (Included cohort reported by Grammer, 1995)
Outcome/Diagnosis	Occupational asthma, allergic rhinitis, occupational asthma-rhinitis, hemorrhagic rhinitis
Activity Intervention	Medical surveillance, removal from exposure (> 1 year) Medical surveillance consisted of symtpom questionnaire, physical examination, spirometry, chest film, and immunological assays at diagnosis and at follow-up.
Participation Rate	Study population consisted of 28 employees identified over a 4-year surveillance period
Intervention Effectiveness	Of 28 subjects, symptoms and spirometry normalized in all except except one who had mild asthma. Statistically significant declines in IgE and IgG were also observed at follow-up. Limitation: no comparison group.