Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Venables
Study Year	1987
Country	UK
Molecular Weight of Agent	LMW
Category	Anhydrides
Agent	Tetrachlorophthalic anhydride (TCPA)
Occupation	Process workers using TCPA (Includes cohort reported by Howe, 1983)
Outcome/Diagnosis	Occupational asthma
Activity Intervention	Removal from exposure (4 years)
Participation Rate	6 of 7 eligible subjects (Participation rate: 86%)
Intervention Effectiveness	One out of 7 subjects died one year after removal. Five of 7 subjects continued with mild bronchial hyperresponsiveness at follow-up. Specific IgE fell exponentially by a half-life of 1-year, but was still detectable at follow-up. Limitation: no comparison group.