| Primary |
| Vanhanen |
| 2000 |
| Norway |
| HMW |
| Biological enzyme |
| Bacillus subtilis derived detergent enzymes (lipase, a-amylase, cellulase) |
| Detergent industry workers |
| Enzyme sensitization |
| Encapsulation of enzyme, dust control (local exhaust ventilation), use of respiratory equipment (1980's) |
| 76 of 80 eligible subjects (Participation rate: 95%) |
| Nine of 40 exposed subjects were sensitized (22%). This is in comparison to the prevelances reported in the detergent industry in the early 1970's that ranged from 5% to 40%. None of the non-exposed workers (n=36) were sensitized. Certain areas of production line had concentrations of protease above ACGIH-TLV. |
