Secondary |
Barker |
1998 |
UK |
LMW |
Anhydrides |
Tetrachlorophthalic anhydride (TCPA) |
Process workers using TCPA (Includes cohort reported by Venables, 1987 and Howe, 1983) |
Occupational asthma |
Removal from exposure (1980, 12 years) |
6 of 6 eligible subjects (Participation rate: 100%) |
From 1984-1992, there were no trends observed in improvement of symptoms, bronchial responsiveness, PEF variability, and in decreased use of inhaled corticosteroids, despite progressive fall of specific IgE (n=6). Limitation: no comparison group. |