Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Conner
Study Year	2002
Country	USA
Molecular Weight of Agent	LMW
Category	Diisocyanates
Agent	Toluene diisocyanate (TDI), mold-release overspray
Occupation	TDI-production plant workers (Includes cohort reported by Ott, 2000)
Outcome/Diagnosis	Occupational asthma
Activity Intervention	Improvement in local exhaust ventilation, engineering controls, medical surveillance Medical surveillance consisted of respiratory questionnaire, spirometry, and physical examination at preplacement and at 1, 3, 6 months afterward. Surveillance is biannual after 6 months until 2 years, when it becomes annual.
Participation Rate	4 of 4 eligible subjects (Participation rate: 100%)
Intervention Effectiveness	After reduction in exposure to mold release overspray following environmental hygiene improvement, subjects identified with OA (n=4) via TDI-medical surveillance resumed former work with no recurrence of respiratory symptoms. Limitation: no comparison group.