Secondary |
Paggiaro |
1984 |
Italy |
LMW |
Diisocyanates |
Toluene diisocyanate (TDI) |
Furniture manufacturing workers |
Asthmatic and non-asthmatic respiratory disease |
Removal from exposure (2 years) |
Limitation: no report of participation rate |
Eight of 12 subjects with asthma reported dyspnea, while wheezing with PFT remain unchanged. Bronchial hyperresponsiveness declined in 3 of 12 subjects. Fifteen subjects with continued exposure experienced a decline in PFT (p<0.05) with 10 of 15 subjects presenting with symptoms of chronic bronchitis. |