Secondary |
Moller |
1986 |
USA |
LMW |
Diisocyanates |
Toluene diisocyanate (TDI) |
Polyurethane foam workers, spray painters, clean-up crew workers |
Occupational asthma |
Removal from exposure (mean: 4.5 years) |
7 of 12 eligible subjects (Participation rate: 58%) |
Six of seven subjects presented with persistent asthma symptoms at follow-up, reporting daily medication use. Limitation: no comparison group. |