| Primary |
| Cullinan |
| 2000 |
| UK |
| HMW |
| Biological enzyme |
| Bacillus subtilis derived detergent enzymes (protease, amylase, cellulase) |
| Detergent industry workers |
| Occupational asthma |
| Encapsulation of enzyme, modern process techniques |
| 350 of 432 eligible subjects (Participation rate: 81%) |
| Estimated total of 56 cases of occupational asthma in the current workforce is considered as high, or higher, than within the industry before encapsulation. Airborne enzyme concentration measurements (n=1767) for the most recent year prior to data collection indicate that 5% of the measurements were above industry guidelines. |
