Prevention of Work-related Asthma: Study Search Results

Study Details
Prevention LevelSecondary
Study Year1992
Molecular Weight of AgentLMW
AgentToluene diisocyanate (TDI)
OccupationWorkers in general population
Outcome/DiagnosisOccupational asthma
Activity InterventionRemoval from exposure (6 months)
Participation RateLimitation: no report of participation rate
Intervention EffectivenessThickness of reticular basement membrane was reduced in all subjects (n=6) at follow-up (p<0.05), to values similar of those for non-asthma control subjects (n=4). Changes in inflammatory cell numbers were not statistically significant. Airway hyperresponsiveness persisted at follow-up in most subjects despite absence of symptoms.
Page last reviewed: May 25, 2022