Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Saetta
Study Year	1992
Country	Italy
Molecular Weight of Agent	LMW
Category	Diisocyanates
Agent	Toluene diisocyanate (TDI)
Occupation	Workers in general population
Outcome/Diagnosis	Occupational asthma
Activity Intervention	Removal from exposure (6 months)
Participation Rate	Limitation: no report of participation rate
Intervention Effectiveness	Thickness of reticular basement membrane was reduced in all subjects (n=6) at follow-up (p<0.05), to values similar of those for non-asthma control subjects (n=4). Changes in inflammatory cell numbers were not statistically significant. Airway hyperresponsiveness persisted at follow-up in most subjects despite absence of symptoms.