Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Pisati
Study Year	1993
Country	Italy
Molecular Weight of Agent	LMW
Category	Diisocyanates
Agent	Toluene diisocyanate (TDI)
Occupation	Workers in general population
Outcome/Diagnosis	Occupational asthma
Activity Intervention	Removal from exposure, transfer to low exposure area, respiratory protection (5 years)
Participation Rate	60 of 65 eligible subjects (Participation rate: 92%)
Intervention Effectiveness	For subjects who transferred (n=17), there were decreases in FEV1 (p<0.01) and PD15 (p<0.001), and increases in symptom score (p<0.001) and medication use (p<0.001). For subjects who ceased exposure (n=43), there was a decrease in symptom score (p<0.001), and an increase in PD15 (p<0.001). More than half (n=22) of those removed from exposure had recovered or improved at follow-up.