Prevention of Work-related Asthma: Study Search Results

Study Details

Prevention Level	Secondary
Author	Saetta
Study Year	1995
Country	Italy
Molecular Weight of Agent	LMW
Category	Diisocyanates
Agent	Toluene diisocyanate (TDI)
Occupation	Workers in general population (Includes cohort reported by Saetta, 1992)
Outcome/Diagnosis	Occuaptional asthma
Activity Intervention	Removal from exposure (range: 6-21 months)
Participation Rate	Limitation: no report of participation rate
Intervention Effectiveness	At follow-up for 10 subjects, decreases were observed for sensitivity to TDI (p<0.05), thickness of subepithelial fibrosis (p<0.007), and numbers of subepithelial fibroblasts (p<0.05), mast cells (p<0.02), and lymphocytes (p<0.03) in comparison with values at diagnosis.