An illness characterized by diarrhea and/or vomiting. Severity is variable.
A clinically compatible illness that is laboratory confirmed
When other cases are known to be occurring, a less than fourfold rise in titer between acute- and convalescent-phase serum may be considered significant. Likewise, a less than fourfold fall between early and late convalescent-phase sera may be important in these circumstances. Only confirmed cases should be reported to the National Notifiable Diseases Surveillance System (NNDSS). Illnesses due to strains of V. cholerae other than toxigenic V. cholerae 01 should not be reported as cases of cholera.