Infection may be asymptomatic or may produce an acute or chronic disease. Although the disease initially resembles an influenza-like or pneumonia-like febrile illness primarily involving the bronchopulmonary system, dissemination can occur to multiple organ systems. An illness is typically characterized by one or more of the following:
A confirmed case must meet at least one of the following laboratory criteria for diagnosis:
A case that meets the clinical criteria and is laboratory confirmed.