Skip directly to search Skip directly to A to Z list Skip directly to navigation Skip directly to page options Skip directly to site content

Granuloma Inguinale (Calymmatobacterium granulomatis)
1997 Case Definition

Clinical Description

A slowly progressive ulcerative disease of the skin and lymphatics of the genital and perianal area caused by infection with Calymmatobacterium granulomatis. A clinically compatible case would have one or more painless or minimally painful granulomatous lesions in the anogenital area.

Laboratory Criteria for Diagnosis

Demonstration of intracytoplasmic Donovan bodies in Wright or Giemsa-stained smears or biopsies of granulation tissue

Case Classification


A clinically compatible case that is laboratory confirmed


The 1997 case definition appearing on this page was previously published in the 1990 MMWR Recommendations and Reports titled Case Definitions for Public Health Surveillance.1,2 Thus, the 1990 and 1997 versions of the case definition are identical.


  1. CDC. (1997). Case Definitions for Infectious Conditions Under Public Health Surveillance. MMWR, 46(RR-10), 1-55.
  2. CDC. (1990). Case Definitions for Public Health Surveillance. MMWR, 39(RR-13), 1-43.