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Hepatitis B, Chronic
2003 Case Definition

Clinical Description

Persons with chronic hepatitis B virus (HBV) infection may be asymptomatic. They may have no evidence of liver disease or may have a spectrum of disease ranging from chronic hepatitis to cirrhosis or liver cancer.

Laboratory Criteria for Diagnosis

  • Hepatitis B surface antigen (HBsAg) positive, total hepatitis B core antibody (anti-HBc) positive (if done) and immunoglobulin M (IgM) anti-HBc negative, OR
  • HBsAg positive two times at least 6 months apart.

Case Classification


A case that is laboratory confirmed.