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Lymphogranuloma Venereum (Chlamydia trachomatis)
1990 Case Definition

Clinical Description

Infection with L1, L2, or L3 serovars of Chlamydia trachomatis may result in a disease characterized by genital lesions, suppurative regional lymphadenopathy, or hemorrhagic proctitis. The infection is usually sexually transmitted.

Laboratory Criteria for Diagnosis

  • Isolation of C. trachomatis, serotype L1, L2, or L3, from clinical specimen, OR
  • Demonstration of inclusion bodies by immunofluorescence in leukocytes of an inguinal lymph node (bubo) aspirate, OR
  • Positive microimmunofluorescent serologic test for a lymphogranuloma venereum strain of C. trachomatis (in a clinically compatible case)

Case Classification


A clinically compatible case with one or more tender fluctuant inguinal lymph nodes or characteristic proctogenital lesions with supportive laboratory findings of a single C. trachomatis complement fixation (CF) titer of greater than 64


A case that is laboratory confirmed