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Streptococcus Pneumoniae, Invasive Disease (Child, <5 Years) (Streptococcus pneumoniae)
2000 Case Definition

Clinical Description

Streptococcus pneumoniae causes many clinical syndromes, depending on the site of infection (e.g., acute otitis media, pneumonia, bacteremia, or meningitis). Starting in 2000, a conjugate pneumococcal vaccine is recommended for prevention of pneumococcal disease in the pediatric population.

Laboratory Criteria for Diagnosis

Isolation of S. pneumoniae from a normally sterile site (e.g., blood, cerebrospinal fluid, or, less commonly, joint, pleural, or pericardial fluid)

Case Classification


A clinically compatible case in a child less than 5 years of age caused by laboratory-confirmed culture of S. pneumoniae from a normally sterile site