β-Lactamase: Negative*
*April 1, 2025
Neisseria gonorrhoeae Reference Isolates is
the new name of a pre-existing panel, with similar name, provided through the
AR Isolate Bank. The identification (ID) convention for the isolates in this
panel has also changed. The changes are applicable only to the naming of the
panel and the isolate IDs. The changes do not affect the physical
characteristics of any reference gonococcal strains in this panel. The changes
are as follow:
i)
New name for this panel is Neisseria gonorrhoeae Reference
Isolates.
ii)
New isolate IDs are NG-F, NG-G, NG-K, NG-L, NG-M, NG-N, NG-O, NG-P,
NG-U, NG-V, NG-W, NG-X, NG-Y, and NG-Z.
The ‘unique letter’ designation in the isolate
IDs (F, G, K, L, M, N, O, P, U, V, W, X, Y, and Z) is transferred over from the
previous panel’s isolate IDs for each isolate (i.e., the ‘new’ Z is the same
strain as the ‘old’ Z). The AR Isolate Bank Number for the gonococcal
strains in this panel are retained and could be used to link back to the
previous naming convention for each isolate. Lastly, the ‘unique letter’ in the
isolate IDs corresponds to the same strain with the same letter assignment
published by Unemo et.al. (2016)#. For questions, or to
request additional information about this announcement, please contact the CDC
& FDA AR Isolate Bank via email at ARbank@cdc.gov.
#https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079299/
MIC results provided were determined by agar dilution.
MIC results for each antimicrobial agent for an isolate may commonly be ± 1 log2 (doubling dilution) different than what is posted on the FDA & CDC AR Bank website because this is the normal technical variability of antimicrobial susceptibility testing (see J. H. Jorgensen. 1993. J Clin Microbiol. Vol 31[11]: 2841-2844).
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