Isolates harboring two or more of the five major carbapenemases (IMP, KPC, NDM, OXA-48-like &VIM). This collection was assembled to challenge detection of these carbapenemases when present in a single strain. Please note: Some of these variants may not reliably be detected by all commercial tests.
To order isolates(s) recently added to this panel, please use the following link:
https://wwwn.cdc.gov/ARIsolateBank/Panel/PanelDetail?ID=1366
Panel ID: MULTI
MICs obtained by broth microdilution. Modal MIC is reported.
MIC results for each antimicrobial agent for an isolate may commonly be ± 1 log2 (doubling dilution) different than what is posted on the FDA & CDC AR Bank website because this is the normal technical variability of antimicrobial susceptibility testing (see J. H. Jorgensen. 1993. J Clin Microbiol. Vol 31[11]: 2841-2844).
Note: This AR Bank panel includes isolates that are pan-resistant, meaning they are susceptible to none of the antimicrobial agents tested which may include those commonly used to treat infections with these organisms. This represents an additional risk to staff working with these organisms and should be considered as part of the receiving facility risk assessment required by the Biosafety Compliance Agreement. The increased difficulty in treatment of any infection with those isolates should also be a consideration in deciding which protocols to use and precautions to take for working with these isolates.
