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Piperacillin-tazobactam +aminoglycosides for Enterobacterales (PTA) (Custom)

A set of Enterobacterales from the Enterobacterales Breakpoint Panel (BIT) and the Carbapenemase Detection Panel (CarbaNP) assembled to perform verification assays for updated CLSI breakpoints.
Panel ID: PTA

MICs obtained by broth microdilution. Modal MIC is reported.

MIC results for each antimicrobial agent for an isolate may commonly be ± 1 log2 (doubling dilution) different than what is posted on the FDA & CDC AR Bank website because this is the normal technical variability of antimicrobial susceptibility testing (see J. H. Jorgensen. 1993. J Clin Microbiol. Vol 31[11]: 2841-2844).

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AR Bank #	Organism	Resistance Mechanisms	Biosample Accession #	Main Panel
0001	Escherichia coli	aac(6')-Ib-cr, aadA5, ACRF, catB4, dfrA17, KPC-3, MDF(A), mph(A), OXA-1, sul1, tet(A), tet(R)	SAMN04014842	Enterobacterales Carbapenem Breakpoint (BIT)
0002	Enterobacter cloacae	aac(6')-Ib, aadA1, ACT-45, aph(3')-Ia, aph(3')-Ib, aph(6)-Id, dfrA14, KPC-3, OmpF2, OXA-9, sul2, TEM-1A	SAMN04014843	Enterobacterales Carbapenem Breakpoint (BIT)
0003	Klebsiella pneumoniae	aac(6')-Ib, aadA1, aph(3')-Ib, aph(6)-Id, dfrA14, EMRD, KDEA, KPC-3, Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-12, sul2, TEM-1A	SAMN04014844	Enterobacterales Carbapenem Breakpoint (BIT)
0004	Klebsiella pneumoniae	aac(6')-Ib, aadA1, aadA2, catA1, dfrA12, EMRD, KDEA, KPC-3, Omp35, OmpK35, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN04014845	Enterobacterales Carbapenem Breakpoint (BIT)
0006	Escherichia coli	aac(3)-IIa, aac(6')-IB3, aadA5, ACRF, aph(3')-Ib, aph(6)-Id, cmlA1, CMY-2, CTX-M-14, dfrA17, EMRD, MDF(A), mph(A), OmpC, OmpC2, OmpF, sul1, sul2, TEM-1, tet(A)	SAMN04014847	Enterobacterales Carbapenem Breakpoint (BIT)
0009	Klebsiella aerogenes	CMY2-MIR-ACT-EC, Omp35, Omp36, OmpK35, OmpK36	SAMN04014850	Enterobacterales Carbapenem Breakpoint (BIT)
0010	Klebsiella pneumoniae	CMY-94, EMRD, fosA, KDEA, Omp35, OmpK35, oqxA, oqxB14, SHV-1	SAMN04014851	Enterobacterales Carbapenem Breakpoint (BIT)
0012	Klebsiella pneumoniae	aac(3)-Iva, aac(6')-Ib, aadA1, aph(4)-Ia, catA1, cmlA1, dfrA12, EMRD, KDEA, Omp35, OmpK35, oqxA, oqxB, SHV-12, sul1, sul3	SAMN04014853	Enterobacterales Carbapenem Breakpoint (BIT)
0013	Escherichia coli	aac(3)-IId, aadA2, catA1, CTX-M-14, dfrA12, EC-5, EMRD, MDF(A), mph(A), sul1, TEM-1, tet(A), tet(R)	SAMN04014854	Enterobacterales Carbapenem Breakpoint (BIT)
0014	Escherichia coli	aac(3)-IIa, aac(6')-Ib-cr, ACRF, catB4, CTX-M-15, EMRD, MDF(A), OXA-1, tet(A), tet(R)	SAMN04014855	Enterobacterales Carbapenem Breakpoint (BIT)
0015	Escherichia coli	aac(3)-IId, aac(6')-Ib-cr, aadA5, ACRF, aph(3')-Ib, aph(6)-Id, catB4, CTX-M-15, dfrA17, EMRD, MDF(A), mph(A), OmpF, OXA-1, sul1, sul2, TEM-1, tet(A), tet(B), tet(R)	SAMN04014856	Enterobacterales Carbapenem Breakpoint (BIT)
0017	Escherichia coli	ACRF, EMRD, MDF(A)	SAMN04014858	Enterobacterales Carbapenem Breakpoint (BIT)
0018	Klebsiella aerogenes		SAMN04014859	Enterobacterales Carbapenem Breakpoint (BIT)
0019	Escherichia coli	ACRF, EC-13, EMRD, MDF(A), TEM-1	SAMN04014860	Enterobacterales Carbapenem Breakpoint (BIT)
0020	Escherichia coli	ACRF, MDF(A)	SAMN04014861	Enterobacterales Carbapenem Breakpoint (BIT)
0022	Citrobacter freundii	CMY-109, QnrB38	SAMN04014863	Enterobacterales Carbapenem Breakpoint (BIT)
0024	Citrobacter koseri	MAL-1	SAMN04014865	Enterobacterales Carbapenem Breakpoint (BIT)
0025	Citrobacter koseri	aac(3)-IId, aadA2, aph(6)-Id, dfrA12, MAL-1, mph(A), strA, sul1, sul2, TEM-1, tet(A), tet(R)	SAMN04014866	Enterobacterales Carbapenem Breakpoint (BIT)
0026	Providencia stuartii	aac(2')-Ia, catA3, QnrD1, tet(B)	SAMN04014867	Enterobacterales Carbapenem Breakpoint (BIT)
0027	Serratia marcescens	aac(6')-SERRA, SDEB, SMDA, SMDB, SME, SRT	SAMN04014868	Enterobacterales Carbapenem Breakpoint (BIT)
0028	Klebsiella oxytoca	aph(3')-Ia, OXY-1-1	SAMN04014869	Enterobacterales Carbapenem Breakpoint (BIT)
0029	Proteus mirabilis	tet(J)	SAMN04014870	Enterobacterales Carbapenem Breakpoint (BIT)
0038	Enterobacter cloacae	aac(3)-IId, aac(6')-Ib, aadA1, aadA2, ACT-17, armA, ble-MBL, catB4, CTX-M-15, dfrA12, floR2, fosA, LAP-2, mph(E), msr(E), NDM-1, Omp36, OmpC, OmpC2, OmpK36, OXA-1, OXA-9, qacEdelta1, QnrS1, rmtB4, sul1, TEM-1, tet(G)	SAMN04014879	Gram Negative Carbapenemase Detection (CarbaNP)
0039	Klebsiella pneumoniae	aac(3)-IId, aac(6')-Ib-cr, aadA1, aadA2, aph(3")-Ib, aph(6)-Id, ARR-2, catA1, CTX-M-15, dfrA12, dfrA14, EMRD, ere(A), fosA5, KDEA, Omp35, OmpK35, oqxB9, oqxB9, OXA-181, qacEdelta1, SHV-26, sul1, sul2, tet(A), tet(R)	SAMN04014880	Gram Negative Carbapenemase Detection (CarbaNP)
0040	Klebsiella pneumoniae	aac(3)-IIa, aac(6')-Ib-cr, aac(6')-Il, aph(3')-Ia, aph(6)-Id, catB4, CTX-M-15, dfrA1, EMRD, KDEA, mph(A), Omp35, OmpK35, oqxA, oqxB25, OXA-1, qacEdelta1, SHV-11, strA, sul1, tet(A), tet(R), VIM-27	SAMN04014881	Gram Negative Carbapenemase Detection (CarbaNP)

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CDC & FDA Antimicrobial Resistance Isolate Bank

Piperacillin-tazobactam +aminoglycosides for Enterobacterales (PTA) (Custom)

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