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Aminoglycoside/tetracycline Resistance (ATR)

A panel of gram-positive and gram-negative bacteria with various molecular mechanisms of resistance to aminoglycoside and tetracycline drugs. This panel can be used to challenge novel aminoglycoside and tetracycline candidates to evaluate for cross-resistance across different drugs in the same class.
Panel ID: ATR

MICs obtained by broth microdilution. Modal MIC is reported.

MIC results for each antimicrobial agent for an isolate may commonly be ± 1 log2 (doubling dilution) different than what is posted on the FDA & CDC AR Bank website because this is the normal technical variability of antimicrobial susceptibility testing (see J. H. Jorgensen. 1993. J Clin Microbiol. Vol 31[11]: 2841-2844).

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AR Bank #	Organism	Resistance Mechanisms	Biosample Accession #
0541	Escherichia coli	aac(6')-Ib-AKT, aadA5, ACRF, catB4, CTX-M-15, dfrA17, EMRD, KPC-3, MDF(A), mph(A), OXA-1, sul1, TEM-1B, tet(A), tet(R)	SAMN11953973
0542	Klebsiella pneumoniae	aac(6')-Ib, aadA2, catA1, dfrA12, EMRD, KDEA, mph(A), oqxA, oqxB, SHV-12, sul1	SAMN11953974
0543	Escherichia coli	aadA1, ACRF, ant(2")-la, CTX-M-15, dfrA36, EC, EMRD, floR, MDF(A), sul1, sul2, TEM-135, tet(A), tet(R)	SAMN11953975
0544	Enterobacter cloacae	aac(6')-Ib, aadA1, ACT-45, aph(3")-Ib, aph(3')-Ia, aph(6)-Id, dfrA14, KPC-3, OXA-9, SHV-12, sul2, TEM-1A	SAMN11953976
0545	Enterobacter cloacae	aac(3)-IIa, aac(6')-Ib-cr, aadA1, ACT-46, aph(3")-Ib, aph(6)-Id, catA1, catB4, CTX-M-15, dfrA14, KPC-2, OXA-1, QnrB1, sul2, TEM-1, tet(A)	SAMN11953977
0546	Escherichia coli	aac(3)-IId, aph(3")-Ib, aph(6)-Id, dfrA17, EC-5, EMRD, KPC-3, MDF(A), sul2, TEM-1, tet(B)	SAMN11953978
0547	Klebsiella aerogenes	aph(6)-Id, dfrA14, sul2	SAMN11953979
0548	Klebsiella pneumoniae	aph(3")-Ib, aph(6)-Id, CTX-M-15, dfrA14, EMRD, fosA, KDEA, KPC-3, oqxA, oqxB20, QnrS1, SHV-28, sul2, TEM-1	SAMN11953980
0549	Escherichia coli	aac(6')-Ib-cr, aadA2, aadA5, ACRF, aph(3")-Ib, aph(6)-Id, catB4, CTX-M-15, dfrA12, dfrA17, EC, EMRD, fosA7.5, MDF(A), mph(A), OXA-1, sul1, sul2, tet(A), tet(B), tet(R)	SAMN11953981
0550	Klebsiella pneumoniae	aadA2, ant(2")-la, catA1, dfrA12, EMRD, KDEA, KPC-3, mph(A), oqxA, oqxB, QnrS1, SHV-189, sul1	SAMN11953982
0551	Escherichia coli	aac(3)-IId, aac(6')-Ib-cr, aadA5, ACRF, aph(3")-Ib, aph(6)-Id, catA1, catB3, CTX-M-15, dfrA17, MDF(A), OXA-1, sul2, TEM-1, tet(B)	SAMN11953983
0552	Klebsiella pneumoniae	aac(6')-Ib, aadA5, aph(3")-Ib, aph(6)-Id, dfrA17, EMRD, KDEA, KPC-2, mph(A), oqxA, oqxB, SHV-11, sul1, sul2, TEM-1, tet(A)	SAMN11953984
0553	Klebsiella pneumoniae	aac(3)-IId, aadA2, armA, CTX-M-15, dfrA12, dfrA14, EMRD, fosA5, KDEA, OXA-181, SHV-26, sul1, sul2	SAMN11953985
0554	Klebsiella pneumoniae	aac(6')-Ib-G, aph(6)-Id, ARR-2, catA2, catB, CTX-M-15, dfrA12, dfrA14, EMRD, KDEA, mph(A), oqxA, oqxB25, OXA-181, QnrB1, rmtF1, SHV-11, sul2, TEM-1	SAMN11953986
0555	Klebsiella pneumoniae	aac(6')-Ib-G, aadA1, aph(3')-Ia, ARR-2, ble-MBL, catB, CTX-M-15, dfrA14, EMRD, KDEA, mph(A), NDM-5, oqxA, oqxB25, OXA-232, OXA-9, QnrS1, rmtF1, SHV-12, sul1, TEM-1A	SAMN11953987
0556	Klebsiella pneumoniae	aac(3)-IIa, aac(6')-Ib, aadA1, CTX-M-15, EMRD, KDEA, oqxA, oqxB20, OXA-48, OXA-9, SHV-100, TEM-1A, tet(D)	SAMN11953988
0557	Klebsiella pneumoniae	aac(6')-Ib-AKT, aadA2, aph(3')-VI, armA, ble-MBL, catB4, CTX-M-15, dfrA1, dfrA12, dfrA14, EMRD, fosA, KDEA, mph(E), msr(E), NDM-1, oqxA, oqxB20, OXA-1, OXA-232, QnrB1, sat2, SHV-28, sul1, TEM-1A, tet(D)	SAMN11953989
0558	Klebsiella pneumoniae	aac(3)-IId, aac(6')-Ib-cr, aadA1, aadA2, armA, ARR-2, catA1, CTX-M-15, dfrA12, dfrA14, EMRD, ere(A), fosA5, KDEA, OXA-181, SHV-26, sul1, sul2, tet(A), tet(R)	SAMN11953990
0559	Escherichia coli	aac(3)-IIa, aac(6')-Ib-cr, aadA5, ACRF, ble-MBL, catB4, CMY-6, dfrA17, MDF(A), mph(A), NDM-1, OXA-1, rmtC, sul1, tet(A), tet(R)	SAMN11953991
0560	Klebsiella pneumoniae	aac(3)-IId, aac(6')-Ib-AKT, aadA1, armA, ARR-2, ble-MBL, catA1, catB4, cmlA5, CMY-4, CTX-M-15, dfrA1, EMRD, ere(A), fosA, KDEA, mph(E), msr(E), NDM-1, oqxA, oqxB20, OXA-1, OXA-9, sat2, SHV-100, sul1, TEM-1A	SAMN11953992
0561	Staphylococcus aureus	aph-STPH, DHA-1, fosB, LMRS, mecA, MEPA, mupA, norA, tet(38), tet(M), Z	SAMN11953993
0562	Staphylococcus aureus	ant(4')-Ia, ant(9)-Ia, aph-STPH, blaI, BLEO, DHA-1, erm(A), fosB, LMRS, LMRS, mecA, MEPA, norA, tet(38), tet(M), Z	SAMN11953994
0563	Staphylococcus aureus	aac(6')-Ie, ant(4')-Ia, aph-STPH, BLEO, DHA-1, fosB, mecA, MEPA, mupA, norA, tet(38)	SAMN11953995
0564	Staphylococcus aureus	aac(6')-Ie, ant(4')-Ia, ant(9)-Ia, aph(3')-IIIa, aph-STPH, blaI, DHA-1, erm(A), fosB, LMRS, mecA, MEPA, mph(C), msr(A), mupA, norA, tet(38), Z	SAMN11953996
0565	Staphylococcus aureus	aac(6')-Ie, ant(9)-Ia, aph(3')-IIIa, aph-STPH, blaI, dfrG, DHA-1, erm(A), fosB, LMRS, mecA, MEPA, norA, sat4, tet(38), tet(K), tet(M), Z	SAMN11953997

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CDC & FDA Antimicrobial Resistance Isolate Bank

Aminoglycoside/tetracycline Resistance (ATR)

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