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Meropenem/vaborbactam Verification (MEV)

A panel of Escherichia coli, Enterobacter cloacae and Klebsiella pneumoniae with different susceptibility to meropenem/vaborbactam. This panel can be used verification and for “in-house” validation of meropenem/vaborbactam antimicrobial susceptibility testing methods.
Panel ID: MEV

MICs obtained by broth microdilution. Modal MIC is reported.

MIC results for each antimicrobial agent for an isolate may commonly be ± 1 log2 (doubling dilution) different than what is posted on the FDA & CDC AR Bank website because this is the normal technical variability of antimicrobial susceptibility testing (see J. H. Jorgensen. 1993. J Clin Microbiol. Vol 31[11]: 2841-2844).

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AR Bank #	Organism	Resistance Mechanisms	Biosample Accession #
1010	Klebsiella pneumoniae	aadA2, aph(3')-Ib, aph(6)-Id, CTX-M-15, dfrA12, KPC-2, mph(A), oqxA, oqxB, QnrS1, SHV-1, sul1, sul2	SAMN16887351
1011	Enterobacter cloacae	aadA2, ACT-16, aph(6)-Id, dfrA12, KPC-2, LAP-2, mph(A), QnrS1, strA, sul1, TEM-1B, tet(A), tet(R)	SAMN16887352
1014	Klebsiella pneumoniae	aac(6')-Ib, aadA1, aph(3')-Ib, aph(6)-Id, dfrA14, KPC-3, Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-12, sul2, TEM-1A	SAMN16887353
1040	Escherichia coli	KPC-2, SHV-12	SAMN16887354
1041	Klebsiella pneumoniae	aac(3)-IIa, aac(6')-Ib, aadA1, aph(3')-VIb, cmlA1, CTX-M-14b, dfrA14, floR, mph(A), Omp35, OmpK35, oqxA, OXA-48, OXA-9, QnrS1, SHV-1, strA, sul3, TEM-1A, tet(D)	SAMN16887355
1042	Enterobacter cloacae	aac(3)-IId, aadA1, aadA2, ACT-7, armA, catB4, CTX-M-15, dfrA12, LAP-2, mph(E), msr(E), NDM-1, Omp36, OmpC, OmpC2, OmpK36, OXA-1, OXA-9, QnrS1, rmtB4, sul1, TEM-1B, tet(G)	SAMN16887356
1043	Klebsiella pneumoniae	aac(6')-Ib, aadA1, aph(3')-Ia, aph(4)-Ia, catA1, cmlA1, dfrA12, KPC-2, mph(A), Omp35, OmpK35, oqxA, oqxB, SHV-11, sul1, sul3	SAMN16887357
1044	Escherichia coli	aac(3)-IIa, aac(6')-IB3, aadA5, aph(3')-Ib, aph(6)-Id, cmlA1, CMY-2, CTX-M-14, dfrA17, mph(A), OmpC, OmpC2, OmpF, sul1, sul2, TEM-1B, tet(A)	SAMN16887358
1045	Klebsiella pneumoniae	aac(3)-IIa, aac(6')-IB3, aadA2, aph(3')-Ia, catA1, CTX-M-2, dfrA12, KPC-2, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-2, SHV-11, sul1, TEM-1B	SAMN16887359
1046	Enterobacter cloacae	aac(6')-Ib, aadA1, aph(3')-Ib, aph(6)-Id, dfrA14, KPC-3, OmpF2, OXA-9, sul2, TEM-1A	SAMN16887360
1047	Klebsiella pneumoniae	aac(6')-Ib, aadA2, aph(3')-Ia, catA1, dfrA12, KPC-3, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN16887361
1048	Escherichia coli	aph(3')-Ib, aph(6)-Id, CTX-M-15, OmpC, OmpC2, OmpK36, OXA-48, sul2, tet(B)	SAMN16887362
1049	Klebsiella pneumoniae	aac(6')-Ib, aadA1, aadA2, aph(3')-Ia, aph(4)-Ia, catA1, cmlA1, dfrA12, KPC-3, mph(A), Omp35, Omp36, OmpC, OmpC2, OmpK35, OmpK36, oqxA, oqxB, OXA-9, SHV-12, sul1, sul3, TEM-1C	SAMN16887363
1050	Enterobacter cloacae	aac(6')-Ib, aadA1, aph(3')-Ia, aph(3')-Ib, aph(6)-Id, dfrA14, KPC-3, OmpF2, OXA-9, sul2, TEM-1A	SAMN16887364
1051	Klebsiella pneumoniae	aac(3)-IIa, aac(3)-IId, aadA2, catB4, CTX-M-15, dfrA12, dfrA14, Omp35, OmpK35, oqxA, oqxB, OXA-1, OXA-48, SHV-11, sul1, TEM-1B, tet(B), tet(D)	SAMN16887365
1052	Klebsiella pneumoniae	dfrA14, KPC-2, oqxA, SHV-12	SAMN16887366
1053	Enterobacter cloacae	aadA1, ACT-7, KPC-2, sul1, TEM-1B, tet(G)	SAMN16887367
1054	Klebsiella pneumoniae	aac(6')-Ib, aadA2, aph(3')-Ia, catA1, dfrA12, KPC-3, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN16887368
1055	Escherichia coli	aac(3)-IIa, aadA2, aadA5, aph(3')-Ib, aph(6)-Id, armA, ARR-2, catA1, catB4, cmlA5, CMY-4, CTX-M-15, dfrA12, dfrA17, dfrA29, ere(A), mph(A), mph(E), msr(E), NDM-1, OmpF, OXA-1, OXA-2, sul1, tet(A), tet(R)	SAMN16887369
1056	Klebsiella pneumoniae	aac(6')-Ib, aadA2, aph(3')-Ia, catA1, dfrA12, KPC-2, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN16887370
1057	Escherichia coli	aac(3)-IId, aac(6')-IB3, aadA1, aph(3')-Ib, aph(3')-VI, aph(6)-Id, catA1, CMY-6, dfrA1, erm(B), NDM-1, OmpF, OXA-1, rmtC, sat-2A, sul1, sul2, TEM-169, tet(B)	SAMN16887371
1058	Klebsiella pneumoniae	aac(6')-Ib, aadA2, aph(3')-Ia, catA1, dfrA12, KPC-2, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN16887372
1059	Escherichia coli	aac(3)-IIa, aac(6')-IB3, aadA5, aph(3')-Ib, aph(6)-Id, cmlA1, CMY-2, CTX-M-14, dfrA17, mph(A), OmpC, OmpC2, OmpF, sul1, sul2, TEM-1B, tet(A)	SAMN16887373
1060	Klebsiella pneumoniae	aac(6')-Ib, aadA2, aph(3')-Ia, catA1, dfrA12, KPC-3, mph(A), Omp35, OmpK35, oqxA, oqxB, OXA-9, SHV-11, sul1, TEM-1A	SAMN16887374
1061	Klebsiella pneumoniae	aac(3)-IIa, aac(6')-Ib, aadA1, CTX-M-15, Omp35, OmpK35, oqxA, OXA-48, OXA-9, SHV-1, TEM-1A, tet(D)	SAMN16887375

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CDC & FDA Antimicrobial Resistance Isolate Bank

Meropenem/vaborbactam Verification (MEV)

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