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  Murray Valley encephalitis   MVEV

Arbovirus

No

3

Results of SALS surveys and information from the Catalogue.
Other Information
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B
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
The three viruses isolated in Melbourne in 1951 from MVE Cases were sent to the Army Medical Service Graduate School at Washington, D.C., because, due to quarantine regulations, the full range of type arboviruses were not available in Australia. The evidence, based on CF and NT tests, indicating that MVE virus is a member of Group B arboviruses, is from reference [9] .
 
Cross Neutralization Tests [9] :
Neutralizing indices (dex)
Test viruses
Rabbit Immune Serum JE MVE/1/51 WN SLE WEE


Japanese Enc. 4.7 1.4 0.5 0.9 0.9
MVE/1/51 1.9 3.6 1.0 1.6 0
WN 1.7 1.0 3.5 1.2 0
SLE 0.9 0.6 1.0 2.4 0
WEE 0.9 1.0 0.1 0.1 3.6
 
Cross-Complement Fixation (9):
Antigen 1:4
Hyperimmune GP Serum JE MVE/1/51 WN SLE WEE


JE 128 32 0 0 0
MVE/1/51 8 64 0 0 0
WN 0 16 64 0 0
SLE 8 16 0 16 0
WEE 0 0 0 0 64
The identification of the New Guinea isolate MVE/1/56 is given in Reference [11] . As far as is known it is not related to any virus not in Group B.
In a cross-neutralization study involving 42 flaviviruses, MVE virus was antigenically placed in a subgroup or complex consisting of JBE, WN, SLE, KUN, USU, KOK, STR, and ALF viruses [25] .
 
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