This study will use innovative statistical methods to examine the temporal patterns in the association between the effects of rescue/recovery work at the World Trade Center (WTC) by FDNY firefighters on the incidence of physician-diagnosed chronic rhinosinusitis (CRS) and on self-reported persistent rhinosinusitis symptoms. Specifically, we will use parametric survival models with change points to determine whether the exposure-response relationship persists for years after exposure or becomes attenuated after some time.
Weakley J, Hall C, Liu X, et al. 2016. The effect of World Trade Center exposure on the latencyy of chronic rhinosinusitis diagnoses in New York City firefighters: 2001–2011. Occupational and Environmental Medicine. 73(4):280–3.
Liu X, Yip J, Zeig-Owens R, et al. 2017. The effect of World Trade Center exposure on the timing of diagnoses of obstructive airway disease, chronic rhinosinusitis, and gastroesophageal reflux disease. Front Public Health. 5:2. (Note: funding support also provided by Project #10726)
