The Stony Brook arm of the WTC Health Program screened 2,400 responders with the Montreal Cognitive Assessment (MoCA), observing a 2.6% moderate-to-severe Cognitive Impairment (scores <20), with significant association with WTC-PTSD. We will use functional MRI and (PET/MRI imaging to examine these brain patterns among 120 SBU-WTC responders, including 30 with CI (MoCA <20) and PTSD, 30 with Cognitive Impairment without PTSD, 30 with normal cognitive functioning (MoCA>26) and PTSD, 30 with normal cognitive functioning without PTSD. All responders will be matched on age and occupation as well as 30 non-WTC exposed, matched controls.
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