The proposed study will investigate the association between World Trade Center exposure and precursor disease for multiple myeloma, monoclonal gammopathy of undetermined significance (MGUS), among WTC Health Program rescue/recovery workers. We demonstrated a significantly higher rate of MGUS in a subset of this population, thus providing a rationale for a comprehensive study in other WTC-exposed rescue/recovery workers. Assessing this association in a heterogeneous cohort will improve the understanding of relationship between WTC exposure and the clinical course of multiple myeloma.
Co-PIs: David Prezant (FDNY) and Carl Landgren (Sloan-Kettering Institute for Cancer Research)
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