Neuropsychological Profile and Neurocognitive Biomarkers of Attention and Memory in Trauma-Exposed Responders at Risk of Premature Cognitive Decline

Project Number
1 U01 OH012272-01
New York State Psychiatric Institute
Fiscal Year Awarded
Project Duration
5 year



Exposure to trauma can lead to premature cognitive decline, as early as mid-life, and adversely affect one’s quality of life. First responders who were 20-35 years old at the time of the September 11 terror attack, are at a greater risk for premature cognitive decline, especially if they have other health consequences such as respiratory disorders or depression. This proposal aims to assess cognitive decline, using a battery of neuropsychological tests and neuroimaging measures, to advance our understanding of premature cognitive decline and its neurobiological mechanisms among the youngest first-responders to hopefully contribute to the development of early interventions.

Study Design: Longitudinal and cross-sectional


No publications available at this time.

Image of Yael  Cycowicz, PhD
Principal Investigator: Yael Cycowicz, PhD
New York State Psychiatric Institute