Chronic kidney disease (CKD) is common, costly and associated with high mortality. A novel area to identify risk factors is mental health disorders, specifically post-traumatic stress disorder (PTSD), commonly observed in WTC responders. We propose to test our hypotheses that severity/course of PTSD can predict the risk of CKD and to identify gene/protein variants that link the pathogenesis of PTSD and CKD in WTC responders. This research will address a knowledge gap of how chronic mental stress contributes to kidney disease in the WTC responders and will lead to further studies on the effects of mental trauma on the kidneys.
Study Design: Retrospective Cohort
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