Sarcoidosis, an inflammatory disease of unknown cause that can affect almost any organ, has been noted in unexpectedly large numbers of World Trade Center (WTC)-exposed persons, including 76 FDNY firefighters. This project is a detailed re-examination of this group, to define their clinical patterns and genetic markers and compare them with those of previously reported non-WTC-exposed sarcoidosis patients. We will also assess genetic differences with similarly WTC-exposed firefighters who did not develop sarcoidosis. The results should help to determine the extent and severity of sarcoidosis triggered by a unique occupational exposure.
Hena KM, Yip J, Jaber N, et al. 2018. Clinical Course of Sarcoidosis in World Trade Center Exposed Firefighters. Chest. 153(1):114-123.
