The objective of this study is to adapt and test an enhanced smoking cessation treatment for World Trade Center (WTC) responders burdened with post-traumatic stress disorder (PTSD) symptoms. We will recruit 100 smokers who have significant PTSD symptoms from the population monitored at the Long Island site of the WTC-Health Program and other responders in the NY metropolitan area with PTSD symptoms. We will over-sample patients with lower respiratory illness to ensure that at least two thirds have these symptoms. Participants are randomly assigned to either: (1) standard smoking cessation or (2) enhanced smoking cessation that addresses PTSD and other anxiety symptoms. Nicotine replacement therapy is administered to both groups.
Zvolensky M, Farris S, Kotov R, et al. 2015. Posttraumatic stress symptoms and smoking among World Trade Center disaster responders: A longitudinal investigation Comprehensive Psychiatry. 63:46–54.
Farris S, Paulus D, Gonzalez A, et al. 2015. Anxiety sensitivity mediates the association between post-traumatic stress symptom severity and interoceptive threat-related smoking abstinence expectancies among World Trade Center disaster-exposed smokers. Addictive Behaviors. 51:204–210.
Farris S, Paulus D, Gonzalez A, et al. 2016. Posttraumatic stress symptoms and body mass index among World Trade Center disaster-exposed smokers: A preliminary examination of the role of anxiety sensitivity. Psychiatry Research. 241:135–140.
Mahaffey B, Gonzalez A, Farris S, et al. 2016. Smoking to regulate negative affect: Disentangling the relationship between posttraumatic stress and emotional disorder symptoms, nicotine dependence, and cessation-related problems. Nicotine & Tobacco Research. 18(6):1471–1478.
Mahaffey B, Gonzalez A, Farris S, et al. 2017. Understanding the connection between posttraumatic stress symptoms and respiratory problems: Contributions of anxiety sensitivity. Journal of Traumatic Stress. 30(1):71–79.
Waszczuk M, Li X, Bromet E, et al. 2017. Pathway from PTSD to respiratory health: Longitudinal evidence from a psychosocial intervention. Health Psychology. 36(5):429–437.
Gonzalez A, Friedberg F, Li X, et al. 2017. Trauma-focused smoking cessation for smokers exposed to the World Trade Center Disaster: a randomized clinical trial. Nicotine & Tobacco Research.
Zvolensky, M., Rodríguez-Canoa, R., Pauluset, D., et al. 2017. Respiratory problems and anxiety sensitivity in smoking lapse among treatment seeking smokers. Addict Behav 75:25–29.