1,4-Dioxane

CAS ID#: 123-91-1

Affected Organ Systems: Cancer, Developmental (effects while organs are developing), Hepatic (Liver), Ocular (Eyes), Renal (Urinary System or Kidneys), Respiratory (From the Nose to the Lungs)

Cancer Classification:  Please contact NTP, IARC, or EPA with questions on cancer and cancer classification.

Chemical Classification: None

Summary: 1,4-Dioxane is a clear liquid that easily dissolves in water. It is used primarily as a solvent in the manufacture of chemicals and as a laboratory reagent; 1,4-dioxane also has various other uses that take advantage of its solvent properties. 1,4-Dioxane is a trace contaminant of some chemicals used in cosmetics, detergents, and shampoos. However, manufacturers now reduce 1,4-dioxane from these chemicals to low levels before these chemicals are made into products used in the home.

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Medical Management Guidelines (MMG) for Acute Chemical Exposure - Medical Management Guideline (MMG) for Acute Chemical Exposure Publication intended to aid emergency department physicians and other emergency healthcare professionals who manage acute exposures.

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Toxicological Profile - Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.

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Page last reviewed: February 10, 2021
Content source: Agency for Toxic Substances and Disease Registry