1,4-Dioxane

CAS ID#: 123-91-1

Affected Organ Systems: Hepatic (Liver), Ocular (Eyes), Renal (Urinary System or Kidneys)

Cancer Classification:  Please contact NTP, IARC, or EPA with questions on cancer and cancer classification.

Chemical Classification: None

Summary: 1,4-Dioxane is a clear liquid that easily dissolves in water. It is used primarily as a solvent in the manufacture of chemicals and as a laboratory reagent; 1,4-dioxane also has various other uses that take advantage of its solvent properties. 1,4-Dioxane is a trace contaminant of some chemicals used in cosmetics, detergents, and shampoos. However, manufacturers now reduce 1,4-dioxane from these chemicals to low levels before these chemicals are made into products used in the home.

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Page last reviewed: February 10, 2021