CDC Home
Centers for Disease Control and Prevention
CDC 24/7: Saving Lives. Protecting People.™
ARBOVIRUS A-Z Index
A
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Q
R
S
T
U
V
W
X
Y
Z
Note: Javascript is disabled or is not supported by your browser. For this reason, some items on this page will be unavailable. For more information about this message, please visit this page:
About CDC.gov
.
Arbovirus Catalog
Browse the Catalog
ArboCat Home
Virus Sections
Virus Name/Prototype
Original Source
Method of Isolation
Virus Properties
Antigenic Relationship
Biologic Characteristics
Natural Host Range
Susceptibility to...
Experimental Infection...
Histopathology
Human Disease
Geographic Distribution
References
Remarks
References
History
Abbreviations
Information Exchange
User Functions
Login to Contribute
Create an Account
Retrieve Password
Virus Name:
Congo
Abbreviation:
CONV
Status
Arbovirus
Select Agent
No
SALS Level
4
SALS Basis
Level assigned to prototype or wild-type virus. A lower level may be recommended for laboratory strains or geographic variants of the virus with well-defined reduced virulence characteristics, as mentioned in the text.
Other Information
Antigenic Group
CHF-CON
Section VI - Biologic Characteristics
Virus Source (all VERTEBRATE isolates)
blood (M)(LV), liver (LV), liver and spleen pool (LV)
Lab Methods of Virus Recovery (ALL ISOLATIONS)
newborn mice and weaning mice
Cell system (a)
Virus passage history (b)
Evidence of Infection
CPE
PLAQUES
Growth Without CPE
Day (c)
Extent (d)
Titer TCD50/ml (e)
Day (c)
Size (f)
Titer PFU/ml (e)
+/- (g)
Produces persistent infection withour CPE in LLC-MK2 cells when media changed regularly. These chronically infected cells after 6-8 transfers were resistant to superinfection (plaque challenge) with Sindbis, Catu, Candiru, Chenuda, Soldado, and Congo viruses but susceptible to VS-Indiana and Cocal viruses (T. Stim. Personal Communication.)
** Expressed in dex
LLC-MK2 (CL)
3010 SM 6 TC 1
5-7
Plaques
4.2**
Vero (CL)
No plaques
Vero (CL)
SM 2
No CPE
4.5**
+
BHK-21 (CL)
No CPE
6.5
+
Ae aegypti (CL)
No CPE
-
Ae albopictus (CL)
No CPE
-
LLC-MK2 (CL)
SM6 BHK 1
4
2+
8.5 (12)
<<<Click on the PDF icon to the left to view a copy of this virus entry in PDF format.
You can get a copy of the PDF viewer by
clicking here.
