Physicochemical
RNA, Single Strand
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(S)
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Buoyant density in CsCl 1.22 gm/cm3 (3). For other detailed
studies on nature and physical properties, see References 4,5,
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(S)
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(S)
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| Stability of Infectivity (effects) |
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<2.0 dex
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5.1 dex (6)
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1:1000
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<2.0 dex
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6.4 dex (7)
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Sens. to trypsin, chymotrypsin, papain, pancreatic lipase,
sodium lauryl sulfate
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| Virion Morphology |
Spherical particles
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48-50 nm; 50-55 nm (20)
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nm
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nm
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EM; negative staining (3); thin-section (20)
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Spiked virions (20); spherical 7 mm capsomere-like
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Cores = 20-22 nm diameter (20)
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| Morphogenesis |
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| Hemagglutination |
Yes
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SMB ext. by borate-KCl, pH 9; acetone-ether, sucrose-acetone
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Goose
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6.0-6.8
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6.4
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4dC, 24dC, 37dC
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24dC, 37dC
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After exp. human passage, virus adapted to nb mice by ic inoc. (8). 3 HA fractions and at least 3 CF's demonstrated and studied (3-5, 9-11).
* Human volunteer ** Other similar agents isolated from same epidemic (1).
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HI, CF, PRNT, immunodiffusion
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After exp. human passage, virus adapted to nb mice by ic inoc. (8). 3 HA fractions and at least 3 CF's demonstrated and studied (3-5, 9-11).
* Human volunteer ** Other similar agents isolated from same epidemic (1).
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