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  Dengue 4   DENV

Arbovirus

No

2

Results of SALS surveys and information from the Catalogue.
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B
Section VI - Biologic Characteristics

Blood (M), liver (M)

Newborn mice; LLC-MK2 and mosquito cell cultures; inoculation of adult mosquitoes.
 
 
Cell system (a) Virus passage history (b) Evidence of Infection
CPE PLAQUES Growth Without CPE
Day (c) Extent (d) Titer TCD50/ml (e) Day (c) Size (f) Titer PFU/ml (e) +/- (g)


Forms plaques in Vero and and LLC-MK2 (CL)(15); RMK (PC) and PS-Y-15 (CL) (16); MA-104 (CL) and MA-111 (CL) (17); forms plaques and produces CPE in PS (CL) (18); produces CPE in BHK-21 (CL) (19); multiplies and/or produces CPE in C6/36 (CL) Aedes albopictus (CL) (20) and AP-61 (CL) (21,22). Forms plaques in Aedes albopictus (23).
 
 
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