Physicochemical
RNA, Single Strand
|
|
1
|
No
|
1300-1400(S)
|
1.1%
|
in membrane
|
|
4 major
|
4 major and an L protein. Additional polypeptides may be
present, but none unequivocally identified (9).
|
|
|
1.14 gm/ml in potassium tartrate
|
46(S)
|
1.32 gm/ml in CsCl
|
(S)
|
|
| Stability of Infectivity (effects) |
|
50%, 4dC, 1 hr
|
<1.7 dex
|
6.3 dex
|
|
|
|
|
|
|
60dC for 1 hr. ttr_aftr_ <1.7 dex. contrl_ttr 6.3 dex
|
|
| Virion Morphology |
Filamentous with some branching
|
130-14000 x ‡ 80 nm
|
nm
|
300-1500nm
|
Negative contrast electron microscopy
|
Regular, 7-10 nm long; envelope present
|
60 x 130-14000 nm; helical
|
|
| Morphogenesis |
Cytoplasm
|
Plasma membrane
|
Extracellular space
|
Yes; characteristic masses of nucleocapsids in cytoplasm
|
|
|
| Hemagglutination |
Not tried
|
|
|
|
|
|
|
*Disease originally contracted in Yambuku. Transported to mission hospital
in Kinshasa.
|
IFA
|
*Disease originally contracted in Yambuku. Transported to mission hospital
in Kinshasa.
|
| |
