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Virus Name:
Ebola
Abbreviation:
EBOV
Status
Probably not Arbovirus
Select Agent
Yes
SALS Level
4
SALS Basis
Results of SALS surveys and information from the Catalogue.
Other Information
DOC Permit Required
Antigenic Group
Marburg
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
Ebola virus is antigenically distinct by IFA test from 10 catalogued arenaviruses, CHF-Congo, yellow fever and RVF.
The weak cross-reactions between Ebola and Marburg by IFA are shown below:
Time after onset
Antigen
Serums
Marburg
Ebola
Convalescent human Zaire (S.M.)
1 month
4
160
Single injection GP Marburg
12 days
>640
5
Single injection GP Ebola
10 days
2
256
Virus isolates from two discrete outbreaks of Ebola hemorrhagic fever were shown to be antigenically distinct serotypes by a sensitive radioimmunoassay [17] .
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