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Virus Name: Altamira

Abbreviation: ALTV

Status
Possible Arbovirus

Select Agent
No

SALS Level
3

SALS Basis
Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.

Other Information

Antigenic Group
Changuinola

Section V - Antigenic Relationship and Lack of Relationship to Other Viruses

Related by CF to Irituia and to other members of the Changuinola group as follows (tests performed at the Institute Evandro Chagas ):

Serum
Antigen	Irituia	Gurupi	Ourem	Caninde	Jamanxi	Altamira


^a Antibody titer/antigen titer
Irituia	16/16 ^a	16/16	>128/16	>128/16	>128/16	16/16
Gurupi	16/16	32/16	>128/16	>128/16	>128/16	16/16
Ourem	4/16	16/16	>128/64	>128/16	>128/16	16/16
Caninde	16/64	16/64	>128/64	>128/64	>128/64	16/16
Jamanxi	8/4	16/4	>128/4	>128/4	>128/16	16/16
Altamira	8/4	16/4	>128/4	>128/4	>128/16	16/16

Results of neutralization tests performed in infant mice (ic route) at the Evandro Chagas Institute were as follows:

Ascitic Fluid or Serum
Virus	Irituia(5i) ^b	Gurupi (5i) ^b	Ourem (4i) ^b	Caninde (5i) ^c	Jamanxi (3i) ^c	Altamira (4i) ^c


^b Ascitic fluid
^c Serum
^d LNI expressed in dex
Irituia	3.0 ^d				<1.0	0.8
Gurupi		2.5			<0.3	<0.3
Ourem			3.9		<1.0	<0.9
Caninde				3.0	0.8	0.4
Jamanxi	0.2	0.3	0	0.5	3.0	0
Altamira	1.1	1.2	1.0	1.0	0.9	<3.1

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