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  Jacareacanga   JACV

Possible Arbovirus

No

3

Isufficient experience with virus; i.e., experience factor from SALS surveys was less than 500 in laboratory facilities with low biocontainment.
Other Information
 

Corriparta
Section V - Antigenic Relationship and Lack of Relationship to Other Viruses
 
No reactions were observed by CF between BeAr 295042 antigen and grouping flurids of A, B, C, Guama, Capim, Bunyamwera, California, Phlebotomus fever, Simbu, Kemerovo, Tacaribe, as well as polyvalents 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 12, Patois, Bwamba, Congo, Quaranfil, Anopheles A, rabies/LCM etc., and GD VII. It did react with homologous serum, polyvalent Palyam and virus strain BeAr 263191 (isolated in 1974). A relationship has been demonstrated with Corriparta and Acado viruses as follows:
 
Complement-Fixation Test
Sera
Antigens BeAr 263191 BeAr 295042 Acado Corriparta Control


b Serum titer/antigen titer; 0 = <4/<4
BeAr 263191 32/16 b 32/16 >=128/256 8/8 0
BeAr 295042 16/16 32/16 >=128/256 8/16 0
Acado 32/16 32/16 >=128/>=256 8/64 0
Corriparta 8/4 16/16 >=128/64 8/16 0
Control 0 0 0 0 0
Neutralization tests performed by the ic route in nb mice showed antigen differences between these agents, as follows:
 
Neutralization Test (ic route)
Sera
Virus BeAr 263191 BeAr 295042 Acado Corriparta


c LNI in dex
BeAr 263191 4.4 c 3.2 3.3 0.8
BeAr 295042 1.9 3.4 1.3 <=0.2
Acado 2.4 <=1.5 3.7 <=1.3
Corriparta 1.6 <=1.2 <=2.0 2.2
 
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