| | | | | Cell system (a) | Virus passage history (b) | Evidence of Infection | | |
|---|
| | CPE | PLAQUES | Growth Without CPE | | |
|---|
| | Day (c) | Extent (d) | Titer TCD50/ml (e) | Day (c) | Size (f) | Titer PFU/ml (e) | +/- (g) | | |
|---|
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| | Lassa virus multiplied to high titer (5.0-6.0 dex PFU/ml) in Vero, mouse L (CL), swine kidney (CL), human embryo kidney (CL), and diploid human embryo lung (CL) cell cultures. The virus multiplied to lower titers (4.0-5.0 dex PFU/ml) in BHK-21 (CL), CV-1 (CL), FL (CL), HEp-2 (CL) and MDCK (CL) cell cultures. No virus multiplication or plaque formation in chick embryo (PC) cell cultures. Virus plaques only in CV-1 and Vero cell cultures (21). | | | | Vero (CL) | | | CPE | | | Plaques (1) | | | | | | Aedes aegypti (CL) | | | | | | | | - (1) | | | | Ae albopictus (CL) | | | | | | | | - (1) | | |
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